Free Baycol Case Evaluation

In August 2001, German drug manufacturer Bayer AG pulled Baycol from the market. Baycol was withdrawn from the market because it has been linked to at least 31 US deaths. Baycol is one of an extraordinarily popular family of cholesterol-lowering drugs called "statins." Baycol was approved in the United States by the FDA in 1997...
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The drug was withdrawn because the FDA had received reports of Baycol patients experiencing severe rhabdomyolysis. Rhabdomyolysis is a condition that causes muscle-cell breakdown (atrophy) and causes muscle pain, weakness, tenderness, malaise, fever, dark urine, nausea and vomiting. Rhabdomyolysis is a potentially life threatening condition.

"While all statins have been associated with very rare reports of rhabdomyolysis, cases of fatal rhabdomyolysis in association with the use of Baycol have been reported significantly more frequently than for other approved statins," the FDA said.

Rhabdomyolysis involves injury to the kidney caused by toxic effects of the contents of muscle cells. Myoglobin is an iron-containing pigment found in the skeletal muscle. When the skeletal muscle is damaged, the myoglobin is released into the bloodstream. It is filtered out of the bloodstream by the kidneys. Myoglobin may occlude the structures of the kidney, causing damage such as acute tubular necrosis or kidney failure. Myoglobin breaks down into potentially toxic compounds, which will also cause kidney failure.


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